METHYLERGONOVINE MALEATE
Methylergonovine maleate salt
CAS: 57432-61-8
Molecular Formula: C24H29N3O6
METHYLERGONOVINE MALEATE - Names and Identifiers
METHYLERGONOVINE MALEATE - Physico-chemical Properties
| Molecular Formula | C24H29N3O6 |
| Molar Mass | 455.5 |
| Density | 1.2744 (rough estimate) |
| Melting Point | 1720C (dec) |
| Boling Point | 561.98°C (rough estimate) |
| Water Solubility | H2O: 25 mg/mL |
| Appearance | Shape neat color white |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.6500 (estimate) |
| Use | Methylergometrine maleate (Methylergonovine maleate) is an ergot alkaloid, an Methysergide active metabolite with vasoconstriction and uterine contraction. Methylergometrine maleate is a potent, selective, orally active 5-HT receptor antagonist with a pA2 value of 9.6. Methylergometrine maleate has anti-migraine and dopaminergic activity and can be used to prevent and control postpartum hemorrhage. |
METHYLERGONOVINE MALEATE - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R62 - Possible risk of impaired fertility |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 1544 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | KE5500000 |
| HS Code | 2939690000 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
METHYLERGONOVINE MALEATE - Introduction
Methylergonovine maleate salt, the chemical name is formergolide maleate, is a compound with medicinal properties.
Properties: Methylergonovine maleate salt is a crystalline powder, often in the form of white or white yellow solid. It is insoluble in water, but more soluble in organic solvents such as ethanol and acetone. It is high in thermal stability.
use: Methylergonovine maleate salt is mainly used in the field of medicine. It is a strong contractile agent and is widely used to control postpartum and postoperative bleeding, especially uterine bleeding. In addition, it can also be used to treat gynecological diseases such as insufficient contractions and habitual abortion.
Preparation: Methylergonovine maleate salt was prepared from ergonovine via methylation reaction. First, ergometrine reacts with methyl iodide to form methylergometrine. Then, the methyergonovine is reacted with maleic acid and crystallized in a solvent to give Methylergonovine maleate salt.
Safety information: Use caution when using Methylergonovine maleate salt. In the course of medication, should be used in strict accordance with the instructions of the doctor, follow the correct dosage. This compound may cause some side effects, such as dizziness, nausea, vomiting, tachycardia, etc. For pregnant women, lactating women, patients with severe renal dysfunction and bleeding tendency should be used with extreme caution. If any discomfort or unusual symptoms appear, you should immediately discontinue use and consult a doctor. During use, closely monitor the patient's vital signs and blood pressure.
Properties: Methylergonovine maleate salt is a crystalline powder, often in the form of white or white yellow solid. It is insoluble in water, but more soluble in organic solvents such as ethanol and acetone. It is high in thermal stability.
use: Methylergonovine maleate salt is mainly used in the field of medicine. It is a strong contractile agent and is widely used to control postpartum and postoperative bleeding, especially uterine bleeding. In addition, it can also be used to treat gynecological diseases such as insufficient contractions and habitual abortion.
Preparation: Methylergonovine maleate salt was prepared from ergonovine via methylation reaction. First, ergometrine reacts with methyl iodide to form methylergometrine. Then, the methyergonovine is reacted with maleic acid and crystallized in a solvent to give Methylergonovine maleate salt.
Safety information: Use caution when using Methylergonovine maleate salt. In the course of medication, should be used in strict accordance with the instructions of the doctor, follow the correct dosage. This compound may cause some side effects, such as dizziness, nausea, vomiting, tachycardia, etc. For pregnant women, lactating women, patients with severe renal dysfunction and bleeding tendency should be used with extreme caution. If any discomfort or unusual symptoms appear, you should immediately discontinue use and consult a doctor. During use, closely monitor the patient's vital signs and blood pressure.
Last Update：2024-04-09 21:01:54
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